CISL Scuola (Confederazione Italiana Sindacati Lavoratori - Scuola) is the union of primary school and kindergarten personnel, secondary school and vocational training of the CISL. It was founded in 1997 by the union of the unions SINASCEL (National Elementary School Union) and SISM (Italian Middle School Union). On the basis of the data defining the representativeness of trade union organizations, due to the number of members and the votes obtained in the last elections for the RSU (2018), the CISL School is currently the most representative trade union in the sector.

In addition to the National Headquarters, there are now 20 regional/interregional structures in Italy and 58 territorial structures, operating on hundreds of service centers.