The University of Macedonia (UOM) is a well-known university both inside and outside of Greece. Education and research covers a broad spectrum, from economic sciences, political studies and business administration to information systems and applied informatics. UOM has an outstanding range of facilities, services and infrastructure to support its vibrant research community. The Research Committee of the university is formed of a group of specialized administrative personnel whose contractual obligations include the supporting of research projects. The Smart Mobile Interactive Learning Environments (SMILE) Laboratory (http://smile.uom.gr/) of the University of Macedonia has as a mission the Development and Training in the area of Mobile Learning. Professor Anastasios A. Economides, the director of SMILE, leads the e-Learning research group that consists of 5 post-doctoral researchers, and several Ph.D. and M.Sc. students.